منابع مشابه
Naloxone: new therapeutic roles.
The narcotic antagonist naloxene, the n-allyl derivative of oxynlorphone, is used widely by anaesthetists to reverse opiate-induced respiratory depression, However, the discovery that there are endogenous opiate-like substances in the central nervous system and other tissues, and that they are involved in regulation of general physiological phenomena, has raised the possibility that naloxone ma...
متن کاملValidated Spectrophtometric Method for Simultaneous Determination of Bupernorphine and Naloxone in Pharmaceutical Dosage Forms
Buprenorphine is a partial mu agonist and kappa antagonist which is used for the treatment of pain and opioid addiction. A mixture of buprenorphine hydrochloride and naloxone hydrochloride has been approved for the treatment of opioid dependence.In this study a third order derivative spectrophotometric method based on zero-crossing technique has been used for the simultaneous determination of b...
متن کاملValidated Spectrophtometric Method for Simultaneous Determination of Bupernorphine and Naloxone in Pharmaceutical Dosage Forms
Buprenorphine is a partial mu agonist and kappa antagonist which is used for the treatment of pain and opioid addiction. A mixture of buprenorphine hydrochloride and naloxone hydrochloride has been approved for the treatment of opioid dependence.In this study a third order derivative spectrophotometric method based on zero-crossing technique has been used for the simultaneous determination of b...
متن کاملValidated Spectrophtometric Method for Simultaneous Determination of Buprenorphine and Naloxone in Pharmaceutical Dosage Forms
Buprenorphine is a partial mu agonist and kappa antagonist which is used for the treatment of pain and opioid addiction. A mixture of buprenorphine hydrochloride and naloxone hydrochloride has been approved for the treatment of opioid dependence. In this study a third order derivative spectrophotometric method based on zero-crossing technique has been used for the simultaneous determination of ...
متن کاملIntranasal naloxone is a viable alternative to intravenous naloxone for prehospital narcotic overdose.
OBJECTIVE To compare the prehospital time intervals from patient contact and medication administration to clinical response for intranasal (IN) versus intravenous (IV) naloxone in patients with suspected narcotic overdose. METHODS This was a retrospective review of emergency medical services (EMS) and hospital records, before and after implementation of a protocol for administration of intran...
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ژورنال
عنوان ژورنال: JAMA
سال: 2021
ISSN: 0098-7484
DOI: 10.1001/jama.2021.8320